This Summary of Research is offered to churches, faith-based organizations, and individuals of faith seeking evidence-based information about the best ways to care for orphans and children separated from parental care. Whether directly providing care in our own communities or partnering with groups overseas to support orphan care ministries and programs, Christians around the world are rising to the Biblical call to respond to the needs of the orphaned and vulnerable. Globally, the need is great and there is no “one right answer” for every situation. There is, however, a growing body of research and evidence-based “lessons learned” to help guide this faith-inspired work.